Recycling and sequential chromatography is a streamlined model of this process. Countercurrent chromatography is understood for its excessive dynamic vary of scalability: milligram to kilogram portions purified chemical components could also be obtained with this technique. The Chemical Record. 3 (3): 133-143. doi:10.1002/tcr.10057. Chemical evaluation. New York: J. Wiley. Chromatographic Science Series Vol 82. New York: CRC Press. 38. Boston: Elsevier Science Ltd. Poppy straw is first pulverized, then washed as many as six to 10 or more occasions in water which may have an acid added to extend solubility, to produce poppy straw concentrate (PSC, often known as concentrate of poppy straw, CPS). Generally, an ionic displacer (or eluter) is added to mobile phase and an ionic retainer is added to the stationary section. In an typical CCC experiment the biphasic solvent system is pre-equilibrated before the instrument is stuffed with the stationary part and equilibrated with the cellular section.

Phase I is already complete with a 2,800 seat amplified corridor and a 300-seat theater for smaller productions. Sutherland, I. A.; Brown, L.; Forbes, S.; Games, G.; Hawes, D.; Hostettmann, קרקעות למכירה K.; McKerrell, E. H.; Marston, A.; Wheatley, D.; Wood, P. (1998). "Countercurrent Chromatography (CCC) and its Versatile Application as an Industrial Purification & Production Process". DeAmicis, Carl; Edwards, Neil A.; Giles, Michael B.; Harris, Guy H.; Hewitson, Peter; Janaway, קרקעות מופשרות למכירה Lee; Ignatova, Svetlana (2011). "Comparison of preparative reversed phase liquid chromatography and countercurrent chromatography for the kilogram scale purification of crude spinetoram insecticide". Ignatova, Svetlana; Wood, Philip; Hawes, David; Janaway, Lee; Keay, כדאיות השקעה בקרקע David; Sutherland, קרקעות למכירה Ian (2007). "Feasibility of scaling from pilot to process scale". Ian A. Sutherland (2007). "Recent progress on the industrial scale-up of counter-present chromatography". Berthod, Alain; Maryutina, Tatyana; Spivakov, Boris; Shpigun, Oleg; Sutherland, Ian A. (2009). "Countercurrent chromatography in analytical chemistry (IUPAC Technical Report)" (PDF). 2009). "Performance comparability using the GUESS mixture to guage counter-current chromatography instruments".

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