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As a result of of these additional roles, medicine that inhibit COX-1 can cause unwanted side effects. COX-2 inhibitors are a type of NSAID that selectively blocks the COX-2 enzyme and never the COX-1 enzyme. The aim of COX-2 inhibitors is to cut back pain and inflammation with out dropping the protection of COX-1 in the gastrointestinal tract. This produces fewer gastrointestinal unintended effects. In 2005, the Fee published a Inexperienced Paper - Promoting the Psychological Well being of the Population as a first response to the World Health Group's Psychological Health Declaration for Europe. In 2013, a Joint Action Mental Well being and Well-being was launched with financial support from the EU Health Programme. It's a three-yr initiative that aims to create a framework for action at European stage and builds on the European Pact for Psychological Health and Well-being.


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